Company Description
AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas – immunology, oncology, neuroscience, and eye care – and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on X, Facebook, Instagram, YouTube, LinkedIn and Tik Tok.
Job Description
Discovery Biotherapeutics and Genetic Medicine (BGM) at Abbvie is seeking a highly motivated and experienced scientist to join its Protein Sciences Analytical Team. This position offers a unique opportunity to contribute to various Discovery Research Therapeutic Areas (TAs) and Projects by providing in-depth analytical and functional characterization of biologics and biopharmaceutical products, such as complex protein antigens, monoclonal antibodies, multi-specifics, and other antibody-like biologics. The ideal candidate will have a strong background in protein analytical characterization, particularly mass spectrometry, to discern protein critical quality attributes (identity, post-translational modifications, physiochemical properties), prior demonstration of innovative problem solving and troubleshooting, and will foster productive collaborations with other functional groups and TAs. This is an excellent opportunity for a motivated scientist to make a significant impact in a collaborative and innovative environment. Join us in bringing innovative medicines to patients!
Key responsibilities:
- Independently develop and execute mass spectrometry workflows for the characterization of biologics and biotherapeutics (intact, reduced, subunit, and peptide mapping)
- Resolve key project challenges by effectively utilizing available analytical tools, information, and technical expertise
- Develop, optimize and execute new analytical methods and techniques to characterize complex proteins/glycoproteins, antigens and novel protein-based therapeutics
- Exhibit scientific initiative and creativity in biologics characterization and screening beyond traditional mAbs to support BGM and TA projects, including multi-specifics, alternative non-Ig scaffolds, and fusion proteins
- Analyze, document, and report data concisely, formulate conclusions, and design follow-on experiments based on multidisciplinary data
- Provide direct mentorship and guidance to junior scientists and team members, fostering their scientific development and growth
- Provide project updates, analyses, and advice to cross-functional teams and senior management
- Present original work internally and at scientific conferences; may author or co-author scientific papers or patents
Qualifications
- BS or MS or PhD in biology, chemistry, biochemistry or related field with typically 10+ (BS), 8+ (MS) or 0+ (PhD) years of experience
- Demonstrated theoretical and practical understanding of scientific discipline with the ability to learn and master innovative technologies
- In-depth experience with various mass spectrometry platforms (Orbitrap and Q-ToF), MS workflows for protein characterization, and MS software applications for analyzing both routine and complex data sets
- Robust analytical knowledge with demonstrated proficiency of various chromatographic and capillary electrophoresis techniques
- Experience in coding/programing and developing automated data solutions is a plus.
- Working knowledge of biophysical and structural methods, such as DLS, DSF, HDX-MS, X-ray crystallography, etc., is a plus
- Direct experience with biologics, monoclonal antibodies and/or protein therapeutics is a plus
- Excellent organizational skills with the capacity to manage multiple projects and tasks simultaneously within timelines
- Goal-oriented team player with excellent verbal and written communication skills and a strong can-do attitude and can operate effectively in a fast-paced, multi-disciplinary environment
Key AbbVie Competencies:
- Builds strong relationships with peers and cross functionally with partners outside of the team to enable high performance.
- Learns fast, grasps the “essence” and can change course quickly when indicated.
- Raises the bar and is never satisfied with the status quo.
- Creates a learning environment, open to suggestions and experimentation for improvement.
- Embraces the ideas of others, nurtures innovation and manages innovation to reality.
Additional Information
Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:
- The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.
- We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.
- This job is eligible to participate in our short-term incentive programs.
Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law.
AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives, serving our community and embracing diversity and inclusion. It is AbbVie’s policy to employ qualified persons of the greatest ability without discrimination against any employee or applicant for employment because of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, sexual orientation, marital status, status as a protected veteran, or any other legally protected group status.
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